Szerző: " Gulya Károly"

Barczánfalvi Gábor Attila; Nyári Tibor András; Tolnai József; Tiszlavicz László; Gulyás Balázs; Gulya Károly: Automated Segmentation and Morphometric Analysis of Thioflavin-S-Stained Amyloid Deposits in Alzheimer's Disease Brains and Age-Matched Controls Using Weakly Supervised Deep Learning.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 26 (15). ISSN 1661-6596 (2025)

Pesti István; Varga Valentin; Qorri Erda; Frank Rita; Kata Diána; Vinga Krisztián; Szarvas Péter Archiblad; Menyhárt Ákos; Gulya Károly; Bari Ferenc; Farkas Eszter: Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and high-throughput RNA sequencing.
BRITISH JOURNAL OF PHARMACOLOGY, 182 (16). pp. 3800-3817. ISSN 0007-1188 (2025)

Pesti István; Barczánfalvi Gábor; Dulka Karolina; Kata Diána; Farkas Eszter; Gulya Károly: Bafilomycin 1A Affects p62/SQSTM1 Autophagy Marker Protein Level and Autophagosome Puncta Formation Oppositely under Various Inflammatory Conditions in Cultured Rat Microglial Cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25 (15). ISSN 1661-6596 (2024)

Szabó Melinda; Lajkó Noémi; Dulka Karolina; Barczánfalvi Gábor; Lőrinczi Bálint; Szatmári István; Mihály András; Vécsei László; Gulya Károly: The kynurenic acid analog SZR104 induces cytomorphological changes associated with the anti-inflammatory phenotype in cultured microglia.
SCIENTIFIC REPORTS, 13 (1). ISSN 2045-2322 (2023)

Kovács Tibor; Szinyákovics Janka; Billes Viktor András; Murányi Gábor; Varga Virginia Beatrix; Bjelik Annamária; Légrádi Ádám; Szabó Melinda; Sándor Sára Anna; Kubinyi Enikő; Szekeres-Paraczky Cecília Kata; Szocsics Péter; Lőke János; Mulder Jun; Gulyás Balázs; Dobolyiné Renner Éva; Palkovits Miklós; Gulya Károly; Maglóczky Zsófia; Vellai Tibor: A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging.
SCIENTIFIC REPORTS, 12 (1). ISSN 2045-2322 (2022)

Francistiová Linda; Klepe Adrián; Curley Géza; Gulya Károly; Dinnyés András; Filkor Kata: Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain.
FRONTIERS IN IMMUNOLOGY, 12. Terjedelem: 19 p-Azonosító: 730088. ISSN 1664-3224 (2021)

Dulka Karolina; Szabó Melinda; Biróné Lajkó Noémi; Belecz István; Hoyk Zsófia; Gulya Károly: Epigenetic Consequences of in Utero Exposure to Rosuvastatin: Alteration of Histone Methylation Patterns in Newborn Rat Brains.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 (7). Terjedelem: 17 p-Azonosító: 3412. ISSN 1661-6596 (2021)

Dulka Karolina; Nacsa Kálmán; Biróné Lajkó Noémi; Gulya Károly: Quantitative morphometric and cell-type-specific population analysis of microglia-enriched cultures subcloned to high purity from newborn rat brains.
IBRO Neuroscience Reports, 10. pp. 119-129. ISSN 2667-2421 (2021)

Légrádi Ádám; Dulka Karolina; Jancsó Gábor; Gulya Károly: Orofacial skin inflammation increases the number of macrophages in the maxillary subregion of the rat trigeminal ganglion in a corticosteroid-reversible manner.
CELL AND TISSUE RESEARCH, 382 (3). pp. 551-561. ISSN 0302-766X (2020)

Biróné Lajkó Noémi; Kata Diána; Szabó Melinda; Mátyás Adrienne; Dulka Karolina; Földesi Imre; Fülöp Ferenc; Gulya Károly; Vécsei László; Mihály András: Sensitivity of Rodent Microglia to Kynurenines in Models of Epilepsy and Inflammation In Vivo and In Vitro: Microglia Activation is Inhibited by Kynurenic Acid and the Synthetic Analogue SZR104.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21 (23). Terjedelem: 15-Azonosító 9333. ISSN 1661-6596 (2020)

Kata Diána; Földesi Imre; Fehér Z. Liliána; Hackler László Jr.; Puskás László G.; Gulya Károly: A novel pleiotropic effect of aspirin: Beneficial regulation of pro- and antiinflammatory mechanisms in microglial cells.
Brain Research Bulletin, 132. pp. 61-74. ISSN 0361-9230 (2017)

Kovács Tibor; Billes Viktor András; Komlos Marcell; Hotzi Bernadette; Manzéger Anna; Tarnóci Anna; Papp Diána; Szikszai Fanni; Szinyákovics Janka; Rácz Ákos; Noszál Béla; Veszelka Szilvia; Walter Fruzsina; Deli Mária Anna; Hackler László, ifj.; Alföldi Róbert; Huzian Orsolya; Puskás László; Liliom Hanna Laura; Tárnok Krisztián; Schlett Katalin; Borsy Adrienn Éva; Welker Ervin; Kovács Attila Lajos; Pádár Zsolt; Erdős Attila; Légrádi Ádám; Bjelik Annamária; Gulya Károly; Gulyás Balázs; Vellai Tibor: The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms.
SCIENTIFIC REPORTS, 7. Paper 42014-17 p. ISSN 2045-2322 (2017)

Billes Viktor András; Kovács Tibor; Hotzi Bernadette; Manzéger Anna; Tagscherer Kinga; Komlós Marcell; Tarnóci Anna; Pádár Zsolt; Erdős Attila; Bjelik Annamaria; Légrádi Ádám; Gulya Károly; Gulyás Balázs; Vellai Tibor: AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease.
JOURNAL OF HUNTINGTONS DISEASE, 5 (2). pp. 133-147. ISSN 1879-6397 (2016)

Szabó Melinda; Dulka Karolina; Gulya Károly: Calmodulin inhibition regulates morphological and functional changes related to the actin cytoskeleton in pure microglial cells.
BRAIN RESEARCH BULLETIN, 120. pp. 41-57. ISSN 0361-9230 (2016)

Kata Diána; Földesi Imre; Fehér Z. Liliána; Hackler László, ifj.; Puskás László; Gulya Károly: Rosuvastatin enhances anti-inflammatory and inhibits pro-inflammatory functions in cultured microglial cells.
NEUROSCIENCE, 314. pp. 47-63. ISSN 0306-4522 (2016)

Gulyás Balázs; Sovago Judit; Gomez-Mancilla Baltazar; Jia Zhisheng; Szigeti Csaba; Gulya Károly: Decrease of mGluR5 receptor density goes parallel with changes in enkephalin and substance P immunoreactivity in Huntington's disease: a preliminary investigation in the postmortem human brain.
BRAIN STRUCTURE & FUNCTION, 220 (5). pp. 3043-3051. ISSN 1863-2653 (2015)

Szigeti Csaba; Bencsik Norbert; Simonka János Aurél; Légrádi Ádám; Kása Péter; Gulya Károly: Long-term effects of selective immunolesions of cholinergic neurons of the nucleus basalis magnocellularis on the ascending cholinergic pathways in the rat: A model for Alzheimer's disease.
BRAIN RESEARCH BULLETIN, 94. pp. 9-16. ISSN 0361-9230 (2013)

Szigeti Csaba; Sántha Péter; Körtvély Elod; Nyári Tibor András; Horváth Viktor József; Deák Éva; Dux Mária; Gulya Károly; Jancsó Gábor: Disparate changes in the expression of transient receptor potential vanilloid type 1 receptor mRNA and protein in dorsal root ganglion neurons following local capsaicin treatment of the sciatic nerve in the rat.
Neuroscience, 201. pp. 320-330. ISSN 0306-4522 (2012)

Gulyás Balázs; Spenger Christian; Beliczai Zsuzsa; Gulya Károly; Kása Péter; Jahan Mahabuba; Jia Zhisheng; Weber Urs; Pfeifer Andrea; Muhs Andreas; Willbold Dieter; Halldin Christer: Distribution and binding of 18F-labeled and 125I-labeled analogues of ACI-80, a prospective molecular imaging biomarker of disease: A whole hemisphere post mortem autoradiography study in human brains obtained from Alzheimer’s disease patients.
Neurochemistry International, 60 (2). pp. 153-162. ISSN 0197-0186 (2012)

Gulyás Balázs; Pavlova Elena; Kása Péter; Gulya Károly; Bakota Lidia; Várszegi Szilvia; Keller Éva; Horváth Mónika Csilla; Nag Sangram; Hermecz Istvá; Magyar Kálmán; Halldin Christer: Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography.
Neurochemistry International, 58 (1). pp. 60-68. ISSN 0197-0186 (2011)

Légrádi Ádám; Várszegi Szilvia; Szigeti Csaba; Gulya Károly: Adult rat hippocampal slices as in vitro models for neurodegeneration: studies on cell viability and apoptotic processes.
Brain Research Bulletin, 84 (1). pp. 39-44. ISSN 0361-9230 (2011)

Budai Dénes; Mészáros Beatrix; Zsigó Andrea; Gulya Károly: Differential inhibition by trifluoperazine of responses of hippocampal CA1 pyramidal cells to NMDA and AMPA in vivo.
Acta Biologica Szegediensis, 55 (2). pp. 295-300. ISSN 1588-385X (2011)

Nagy Anett Júlia; Berényi Antal; Gulya Károly; Norita Masao; Benedek György; Nagy Attila: Direct projection from the visual associative cortex to the caudate nucleus in the feline brain.
Neuroscience Letters, 503 (1). pp. 52-57. ISSN 0304-3940 (2011)

Keresztes Attila; Birkás Erika; Páhi Annamária; Tóth Géza; Bakota Lidia; Gulya Károly; Szűcs Mária: Pharmacology of a new tritiated endomorphin-2 analog containing the proline mimetic cis-2-aminocyclohexanecarboxylic acid.
Peptides, 32 (4). pp. 722-728. ISSN 0196-9781 (2011)

Tőkés Tünde; Erős Gábor; Bebes Attila; Hartmann Petra; Várszegi Szilvia; Varga Gabriella; Kaszaki József; Gulya Károly; Ghyczy Miklós; Boros Mihály: Protective effects of a phosphatidylcholine-enriched diet in lipopolysaccharide-induced experimental neuroinflammation in the rat.
Shock, 36 (5). pp. 458-465. ISSN 1073-2322 (2011)

Birkás Erika; Bakota Lidia; Gulya Károly; Wen Ting; Pintar John; Tóth Géza; Szűcs Mária: A comprehensive study on the putative delta-opioid receptor (sub)types using the highly selective delta-antagonist, Tyr-Tic-(2S,3R)-beta-MePhe-Phe-OH.
Neurochemistry International, 59 (2). pp. 192-201. ISSN 0197-0186 (2011)

Gulyás Balázs; Brockschnieder Damian; Nag Sangram; Pavlova Elena; Kása Péter; Beliczai Zsuzsa; Légrádi Ádám; Gulya Károly; Thiele Andrea; Dyrks Thomas; Halldin Christer: The norepinephrine transporter (NET) radioligand (S,S)-[18F]FMeNER-D2 shows significant decreases in NET density in the human brain in Alzheimer’s disease: a post-mortem autoradiographic study.
NEUROCHEMISTRY INTERNATIONAL, 56 (6-7). pp. 789-798. ISSN 0197-0186 (2010)

Vizi Sándor; Bagosi Andrea; Krisztin-Péva Beáta; Gulya Károly; Mihály András: Repeated 4-aminopyridine seizures reduce parvalbumin content in the medial mammillary nucleus of the rat brain.
Molecular Brain Research, 131 (1-2). pp. 110-118. ISSN 0169-328X (2004)

Gulya Károly; Szikra J; Kása Péter: Delta opioid system regulates endogenous metal ion contents in rat striatum and medulla.
LIFE CHEMISTRY REPORTS, 11. pp. 125-139. ISSN 0278-6281 (1994)

Gulya Károly; Szikra J.; Lengyel Z.; Harkány T.; Kása Péter: Interaction between the endogenous opioid system and the aluminum content in rat striatum.
In: Recent advances in aging science. Monduzzi, Bologna, pp. 631-635. (1993) ISBN 8832307049

Gulya Károly; Rakonczay Zoltán; Kása Péter: Cholinotoxic effects of aluminum in rat brain.
JOURNAL OF NEUROCHEMISTRY, 54 (3). pp. 1020-1026. ISSN 0022-3042 (1990)

Hoffman Paula L.; Ishizawa Hideaki; Giri P. Rathna; Dave Jitenda R.; Gran Kathleen A.; Liu Li-Ing; Gulya Károly; Tabakoff Boris: The role of arginine vasopressin in alcohol tolerance.
ANNALS OF MEDICINE, 22 (4). pp. 269-274. ISSN 0785-3890 (1990)

Gulya Károly; Simonka J. A.; Kása Péter: Transport of muscarinic cholinergic marker protein activities in regenerating sciatic nerve of rat.
JOURNAL OF NEUROCHEMISTRY, 53 (1). pp. 179-182. ISSN 0022-3042; 1471-4159 (1989)

Roeske William R.; Wang Jian Xin; Gulya Károly; Korc Murray; Serra Mariangela; Ackerman Martha; Mei Lin; Vickroy Thomas; Watson Mark; Yamamura Henry I.: Biochemical, functional and anatomic evidence for putative muscarinic receptor subtypes using selective antagonists (3H)AF-DX 116 and (3H)pirenzepine.
In: Cellular and Molecular Basis for Cholinergic Function. Ellis Horwood series in biomedicine . Horwood Publishing Ltd, Chichester, pp. 64-71. (1987) ISBN 9780895735829; 9783527265633; 0895735822

Watson Mark; Roeske William R.; Vickroy Thomas W.; Smith Thomas L.; Akiyama Kazufumi; Gulya Károly; Duckles Sue P.; Serra Mariangela; Adem Abdu; Nordberg Agneta; Gehlert Donald R.; Wamsley James K.; Yamamura Henry I.: Biochemical and functional basis of putative muscarinic receptor subtypes and its implications.
TRENDS IN PHARMACOLOGICAL SCIENCES, 1986 (Suppl. S.). pp. 46-55. ISSN 0165-6147; 1873-3735 (1986)

Gulya Károly; Pelton J. T.; Gehlert D. R.; Wamsley J. K.; Duckles S. P.; Hruby V.; Yamamura H. I.: Conformationally restricted penicillamine analogs with high selectivity for delta and mu opioid receptors.
In: Neural and Endocrine Peptides and Receptors. Springer New York; Plenum Press, New York, London, pp. 567-580. (1986) ISBN 9781468451542

Pelton John T.; Kazmierski Wieslaw; Gulya Károly; Yamamura Henry I.; Hruby Victor J.: Design and synthesis of conformationally constrained somatostatin analogs with high potency and specificity for mu opioid receptors.
JOURNAL OF MEDICINAL CHEMISTRY, 29 (11). pp. 2370-2375. ISSN 0022-2623; 1520-4804 (1986)

Gulya Károly; Watson M.; Vickroy T. W.; Roeske W. R.; Perry R.; Perry E.; Duckles S. P.; Yamamura H. I.: Examination of cholinergic and neuropeptide receptor alterations in senile dementia of Alzheimer's type (SDAT).
In: Alzheimer's and Parkinson's diseases : Strategies for Research and Development. [Proceedings of the thirtieth OHOlO Conference on Basic and Therapeutic Strategies in Alzheimer's and Other Related Neuropsychiatric Disorders]. ADVANCES IN BEHAVIORAL BIOLOGY (29). Plenum Press, New York, London, pp. 109-116. (1986) ISBN 9781461292838

Gulya Károly; Gehlert Donald R; Wamsley James K; Mosberg Henry I; Hruby Victor J; Yamamura Henry I: Light microscopic autoradiographic localization of delta opioid receptors in the rat brain using a highly selective bis-penicillamine cyclic enkephalin analog.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 238 (2). pp. 720-726. ISSN 0022-3565 (1986)

Pelton John T.; Cody Wayne L.; Hruby Victor J.; Gulya Károly; Hirning Lane D.; Yamamura Henry; Burks Thomas F.: Conformation and design of cyclic somatostatin analogs with high affinity for mu-opiate receptors.
In: Peptides: Structure and Function. Pierce Chemical Co., Rockford (IL), pp. 623-626. (1985) ISBN 0935940049

Kása Péter; Dames W.; Rakonczay Zoltán; Gulya Károly; Joó Ferenc; Wolff J. R.: Modulation of the acetylcholine system in the superior cervical ganglion of rat: Effects of GABA and hypoglossal nerve implantation after in vivo GABA treatment.
JOURNAL OF NEUROCHEMISTRY, 44 (5). pp. 1363-1372. ISSN 0022-3042 (1985)

Gulya Károly; Budai D.; Kása Péter; Rakonczay Zoltán: In vivo effects of ß-bungarotoxin on the acetylcholine system in different brain areas of rat.
JOURNAL OF NEUROCHEMISTRY, 43 (1). pp. 112-119. ISSN 0022-3042 (1984)

Dóczi Tamás Péter; Szerdahelyi Péter; Gulya Károly; Kiss József: Brain water accumulation after central administration of vasopressin.
NEUROSURGERY, 11 (3). pp. 402-407. ISSN 0148-396X (1982)

Kása Péter; Bánsághy K.; Rakonczay Zoltán; Gulya Károly: Postnatal development of the acetylcholine system in different parts of the rat cerebellum.
JOURNAL OF NEUROCHEMISTRY, 39 (6). pp. 1726-1732. ISSN 0022-3042 (1982)

Simonka János Aurél; Gulya Károly: Új módszer a kísérletes idegvarratok pásztázó elektronmikroszkópos vizsgálatára.
KÍSÉRLETES ORVOSTUDOMÁNY, 34. pp. 498-502. ISSN 0023-1878 (1982)

Gulya Károly; Szepesy Gábor; Bánsághy Katalin; Kása Péter: Az acetilkolin tartalom és a szinaptikus vezikulák számának regulációja a központi idegrendszerben [Regulation of acetylcholine content and number of synaptic vesicles in the CNS].
KÍSÉRLETES ORVOSTUDOMÁNY, 33 (4). pp. 362-368. ISSN 0023-1878 (1981)

Gulya Károly; Szepesy G; Bánsághy K: Effects of NVP on the cholinergic system and on the number of synaptic vesicles of rat cerebellum.
In: Drugs, biochemistry and metabolism : Colloquium. Magyar Kémikusok Egyesülete Biokémiai Szakosztály, Budapest, pp. 57-60. (1981) ISBN 9638191201